[dnanian]

Yes, you should first properly partition the drive for the Mac (use the Partition tab in Disk Utility, "Mac OS Extended (Journaled)" as the format type, and make sure to click Options and set the right partition type, too.

Then, use "Backup - all files" with "Erase, then copy" or "Smart Update" to copy the drive. I suggest naming it the same as the original drive. Swap drives and you should be all set.