[dnanian]

You'd basically do this as a backup and restore operation (or, if you put both disks in the MacPro, just a backup). Any "copy protected" applications (many video/music applications fall into this category) will need to be de-authorized and re-authorized on the new drive.

You'll need to properly partition the new drive as "GUID", using the "Mac OS Extended (Journaled)" as the format. Also, name the new drive the SAME as the original drive, and remove the old drive before starting up from the new one.